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POLE4 antibody (N-Term)

POLE4 Reactivity: Human, Cow, Dog, Horse, Guinea Pig, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781088
  • Target See all POLE4 Antibodies
    POLE4 (Polymerase (DNA-Directed), epsilon 4 (p12 Subunit) (POLE4))
    Binding Specificity
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Cow, Dog, Horse, Guinea Pig, Rat
    Host
    • 10
    • 1
    Rabbit
    Clonality
    • 11
    Polyclonal
    Conjugate
    • 8
    • 1
    • 1
    • 1
    This POLE4 antibody is un-conjugated
    Application
    • 7
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Sequence
    MAAAAAAGSG TPREEEGPAG EAAASQPQAP TSVPGARLSR LPLARVKALV
    Predicted Reactivity
    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Rat: 79%
    Characteristics
    This is a rabbit polyclonal antibody against POLE4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human POLE4
    Top Product
    Discover our top product POLE4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 117 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    POLE4 (Polymerase (DNA-Directed), epsilon 4 (p12 Subunit) (POLE4))
    Alternative Name
    POLE4 (POLE4 Products)
    Synonyms
    2400007P05Rik antibody, 5830430F06Rik antibody, YHHQ1 antibody, p12 antibody, DNA polymerase epsilon 4, accessory subunit antibody, polymerase (DNA-directed), epsilon 4, accessory subunit antibody, polymerase (DNA-directed), epsilon 4 (p12 subunit) antibody, Pole4 antibody, POLE4 antibody, pole4 antibody
    Background
    POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
    Alias Symbols: p12, YHHQ1
    Protein Interaction Partner: NFYB, gag-pol, NUP133, POLE3, MAP3K7, UBC, YEATS2, POLE4, UBE3A, HSPA13, POLE2, POLE, RAD17,
    Protein Size: 117
    Molecular Weight
    12 kDa
    Gene ID
    56655
    NCBI Accession
    NM_019896, NP_063949
    UniProt
    Q9NR33
    Pathways
    DNA Damage Repair
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