GATAD2B antibody (N-Term)
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- Target See all GATAD2B Antibodies
- GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GATAD2B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MDRMTEDALR LNLLKRSLDP ADERDDVLAK RLKMEGHEAM ERLKMLALLK
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against GATAD2B. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human GATAD2B
- Top Product
- Discover our top product GATAD2B Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 593 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))
- Alternative Name
- GATAD2B (GATAD2B Products)
- Synonyms
- GATAD2B antibody, MRD18 antibody, P66beta antibody, RP11-216N14.6 antibody, p68 antibody, AL118180 antibody, C430014D17Rik antibody, mKIAA1150 antibody, RGD1308533 antibody, GATA zinc finger domain containing 2B antibody, GATAD2B antibody, gatad2b antibody, Gatad2b antibody
- Background
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Hp66beta (GATAD2B), previously identified as a component of the human MeCP1 complex, is a second member of a p66 gene family (hp66alpha and hp66beta). Both proteins interact with MBD2 and MBD3 functionally and biochemically. Both factors function in synergy, since knocking-down p66alpha affects the repressive function of p66beta and vice versa. Furthermore, confocal microscopy shows a nuclear colocalization of hp66alpha with hp66beta and MBD2 in a speckled pattern. These two highly related mammalian p66 proteins display overlapping functions and are involved in methylation dependent transcriptional repression.
Alias Symbols: P66beta, RP11-216N14.6
Protein Interaction Partner: USHBP1, CEP70, RPGRIP1, TEX11, MBD3, TRIM27, PRKAB2, GOLGA2, CALCOCO2, TRAF1, SUMO2, UBC, ZBTB1, SUZ12, EED, RNF2, HDAC2, HDAC1, SMAD2, MTA3, NOTCH1, MTA2, MTA1, NDUFA7, NDUFA2, SOX2, PARK7, tat, HIST1H4A, HIST1H3A, HIST2H2BE, HIST2H2AC, RBBP7, RBBP4, Fox
Protein Size: 593 - Molecular Weight
- 65 kDa
- Gene ID
- 57459
- NCBI Accession
- NM_020699, NP_065750
- UniProt
- Q8WXI9
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