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PAM antibody (N-Term)

PAM Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781297
  • Target See all PAM Antibodies
    PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))
    Binding Specificity
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 22
    • 10
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit
    Host
    • 18
    • 3
    • 1
    Rabbit
    Clonality
    • 21
    • 1
    Polyclonal
    Conjugate
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAM antibody is un-conjugated
    Application
    • 11
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    PKGVGFRVGG ETGSKYFVLQ VHYGDISAFR DNNKDCSGVS LHLTRLPQPL
    Predicted Reactivity
    Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against PAM. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PAM
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    Discover our top product PAM Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 974 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PAM (Peptidylglycine alpha-Amidating Monooxygenase (PAM))
    Alternative Name
    PAM (PAM Products)
    Synonyms
    PAL antibody, PHM antibody, pal antibody, phm antibody, pamb antibody, CG3832 antibody, Dmel\\CG3832 antibody, dPHM antibody, AE-I antibody, PAL-A antibody, PHM-A antibody, pama antibody, si:dkeyp-35f12.2 antibody, peptidylglycine alpha-amidating monooxygenase antibody, peptidylglycine alpha-amidating monooxygenase S homeolog antibody, Peptidylglycine-alpha-hydroxylating monooxygenase antibody, peptidylglycine alpha-amidating monooxygenase L homeolog antibody, PAM antibody, Pam antibody, pam.S antibody, CHLREDRAFT_150435 antibody, sce7070 antibody, pam antibody, Phm antibody, pam.L antibody
    Background
    PAM is a multifunctional protein. It has two enzymatically active domains with catalytic activities-peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products.This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known.
    Alias Symbols: PAL, PHM
    Protein Interaction Partner: UBC, CALM1, UHMK1, RASSF9, KALRN, TSC2, PRKCA, TSC1,
    Protein Size: 974
    Molecular Weight
    108 kDa
    Gene ID
    5066
    NCBI Accession
    NM_000919, NP_000910
    UniProt
    A6NMR0
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