SLC5A5 antibody (N-Term)

Catalog No. ABIN2781542

Product Details anti-SLC5A5 Antibody

Target: SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC5A5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TAVGGMKAVV WTDVFQVVVM LSGFWVVLAR GVMLVGGPRQ VLTLAQNHSR

Predicted Reactivity: Horse: 79%, Human: 100%, Mouse: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SLC5A5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC5A5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 643 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC5A5

Target: SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))

Alternative Name: SLC5A5 (SLC5A5 Products)

Synonyms: Na(+)/I(-) cotransporter antibody, Na(+)/I(-) symporter antibody, Nis antibody, solute carrier family 5 member 5 antibody, Slc5a5 antibody

Background: The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones.
Alias Symbols: NIS, TDH1
Protein Interaction Partner: ERBB2IP, SLC5A5,
Protein Size: 643

Molecular Weight: 69 kDa

Gene ID: 6528

NCBI Accession: NM_000453, NP_000444

UniProt: Q92911