ATP1B2 antibody (N-Term)

Catalog No. ABIN2782135

This Rabbit Polyclonal antibody specifically detects ATP1B2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been mentioned in 2+ publications

Quick Overview for ATP1B2 antibody (N-Term) (ABIN2782135)

Target: ATP1B2 (ATPase, Na+/K+ Transporting, beta 2 Polypeptide (ATP1B2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1B2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATP1B2 Antibody

Binding Specificity: N-Term

Sequence: WVMLQTVSDH TPKYQDRLAT PGLMIRPKTE NLDVIVNISD TESWGQHVQK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against Atp1b2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 290 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ATP1B2 antibody (ABIN2782135)

Li, Ji, Zhong, Lin, Lv, Hu, Wang: "1-deoxynojirimycin inhibits glucose absorption and accelerates glucose metabolism in streptozotocin-induced diabetic mice." in: Scientific reports, Vol. 3, pp. 1377, (2013) (PubMed).

Li, Ji, Zhong, Lv, Lin: "Cooperative anti-diabetic effects of deoxynojirimycin-polysaccharide by inhibiting glucose absorption and modulating glucose metabolism in streptozotocin-induced diabetic mice." in: PLoS ONE, Vol. 8, Issue 6, pp. e65892, (2013) (PubMed).

Target Details for ATP1B2

Target: ATP1B2 (ATPase, Na+/K+ Transporting, beta 2 Polypeptide (ATP1B2))

Alternative Name: Atp1b2

Background: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The exact function of the beta-2 subunit is not known.
Alias Symbols: Amog, Atpb-2
Protein Size: 290

Molecular Weight: 33 kDa

Gene ID: 11932

NCBI Accession: NM_013415, NP_038201

UniProt: P14231

Pathways: Thyroid Hormone Synthesis