GART antibody (Middle Region)

Catalog No. ABIN2782352

Product Details anti-GART Antibody

Target: GART (Phosphoribosylglycinamide Formyltransferase (GART))

Binding Specificity: Middle Region

Reactivity: Human, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GART antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VLKNGSLTNH FSFEKKKARV AVLISGTGSN LQALIDSTRE PNSSAQIDIV

Predicted Reactivity: Horse: 83%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against GART. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GART

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1010 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GART

Target: GART (Phosphoribosylglycinamide Formyltransferase (GART))

Alternative Name: GART (GART Products)

Synonyms: Gaps antibody, Prgs antibody, AIRS antibody, GARS antibody, GART-A antibody, gart antibody, phosphoribosylglycinamide formyltransferase antibody, phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase antibody, phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase L homeolog antibody, Gart antibody, GART antibody, gart.L antibody

Background: The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: AIRS, GARS, GARTF, MGC47764, PAIS, PGFT, PRGS
Protein Interaction Partner: UBC, SUMO2, SUMO3, NEDD8, SUMO1, SAMHD1, SWAP70, XPO7, FAF1, FARSB, RANBP3, HIRIP3, ZYX, SF1, UGP2, SUPT5H, TROVE2, SET, RPL24, PPAT, PLOD2, HSPA4, XRCC6, CARS, FBXO6, PXN, KPNA2, FN1, SEPHS1, PAICS, WARS, CUL3, CUL5, SIRT7, ELAVL1, GART, ARF6,
Protein Size: 1010

Molecular Weight: 108 kDa

Gene ID: 2618

NCBI Accession: NM_000819, NP_000810

UniProt: P22102