MRPL39 antibody (N-Term)

Catalog No. ABIN2782562

This Rabbit Polyclonal antibody specifically detects MRPL39 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for MRPL39 antibody (N-Term) (ABIN2782562)

Target: MRPL39 (Mitochondrial Ribosomal Protein L39 (MRPL39))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL39 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPL39 Antibody

Binding Specificity: N-Term

Purpose: MRPL39 Antibody - N-terminal region

Sequence: TELTEMRNDL FNKEKARQLS LTPRTEKIEV KHVGKTDPGT VFVMNKNIST

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against MRPL39. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MRPL39

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46256-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL39

Target: MRPL39 (Mitochondrial Ribosomal Protein L39 (MRPL39))

Alternative Name: MRPL39

Background:

Background Information: Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. MRPL39 is a 39S subunit protein. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.

Gene Name: Mitochondrial ribosomal protein L39

Alternative Symbols: L5mt, L39mt, MRPL5, RPML5, MRP-L5, PRED22, PRED66, MSTP003, C21orf92

Protein Name: 39S ribosomal protein L39, mitochondrial

Molecular Weight: 39kDa

Gene ID: 54148

NCBI Accession: NP_059142

UniProt: Q9NYK5