MCCC2 antibody (C-Term)

Catalog No. ABIN2782579

The Rabbit Polyclonal anti-MCCC2 antibody is suitable to detect MCCC2 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for MCCC2 antibody (C-Term) (ABIN2782579)

Target: MCCC2 (Methylcrotonoyl-CoA Carboxylase 2 (Beta) (MCCC2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCCC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MCCC2 Antibody

Binding Specificity: C-Term

Purpose: MCCC2 Antibody - C-terminal region

Sequence: RKVVRNLNYQ KKLDVTIEPS EEPLFPADEL YGIVGANLKR SFDVREVIAR

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against MCCC2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human MCCC2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46313-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MCCC2

Target: MCCC2 (Methylcrotonoyl-CoA Carboxylase 2 (Beta) (MCCC2))

Alternative Name: MCCC2

Background:

Background Information: This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.

Gene Name: methylcrotonoyl-CoA carboxylase 2

Alternative Symbols: MCCB, MCCCbeta

Protein Name: methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

Molecular Weight: 36kDa

Gene ID: 64087

NCBI Accession: NP_071415

UniProt: Q9HCC0