ATP1B4 antibody (Middle Region)

Catalog No. ABIN2782764

Product Details anti-ATP1B4 Antibody

Target: ATP1B4 (ATPase, Na+/K+ Transporting, beta 4 Polypeptide (ATP1B4))

Binding Specificity: Middle Region

Reactivity: Rat, Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1B4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ACQFKRSFLK NCSGLEDPTF GYSTGQPCIL LKMNRIVGFR PELGDPVKVS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ATP1B4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATP1B4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 353 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATP1B4

Target: ATP1B4 (ATPase, Na+/K+ Transporting, beta 4 Polypeptide (ATP1B4))

Alternative Name: ATP1B4 (ATP1B4 Products)

Synonyms: 1110020B02Rik antibody, Ac2-628 antibody, ATPase, (Na+)/K+ transporting, beta 4 polypeptide antibody, ATPase Na+/K+ transporting family member beta 4 antibody, ATPase, Na+/K+ transporting, beta 4 polypeptide L homeolog antibody, Atp1b4 antibody, ATP1B4 antibody, atp1b4.L antibody

Background: This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: -
Protein Size: 353

Molecular Weight: 41 kDa

Gene ID: 23439

NCBI Accession: NM_012069, NP_036201

UniProt: Q9UN42

Pathways: Thyroid Hormone Synthesis, Proton Transport