RNF213 antibody (N-Term)

Catalog No. ABIN2783078

Product Details anti-RNF213 Antibody

Target: RNF213 (Ring Finger Protein 213 (RNF213))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF213 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ETGNNSVQTV FQGTLAATKR WLREVFTKNM LTSSGASFTY VKEIEVWRRL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against RNF213. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human RNF213

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RNF213

Target: RNF213 (Ring Finger Protein 213 (RNF213))

Alternative Name: RNF213 (RNF213 Products)

Synonyms: RNF213 antibody, ALO17 antibody, C17orf27 antibody, KIAA1618 antibody, MYMY2 antibody, MYSTR antibody, NET57 antibody, RGD1308168 antibody, 6030403J01 antibody, D11Ertd759e antibody, mKIAA1554 antibody, E3 ubiquitin-protein ligase RNF213 antibody, ring finger protein 213 antibody, LOC509283 antibody, LOC100626814 antibody, RNF213 antibody, LOC100461067 antibody, Rnf213 antibody

Background: This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2,17)(p23,q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8,17)(q24,q25) translocation has been identified with the MYC gene on chromosome 8.
Alias Symbols: -
Protein Interaction Partner: KRT40, UBXN11, TRIP6, TRIM27, REL, GOLGA2, TRIM23, UBC, RNF213, EGFR, PLAC9, CBX2, vpu, CBX6, CBX4, tat,
Protein Size: 1063

Molecular Weight: 118 kDa

Gene ID: 57674

NCBI Accession: NM_020954, NP_066005