PTGDS antibody (N-Term)

Catalog No. ABIN2783248

The Rabbit Polyclonal anti-PTGDS antibody has been validated for WB and IHC. It is suitable to detect PTGDS in samples from Human, Mouse, Rat, Dog, Horse, Rabbit and Guinea Pig.

Quick Overview for PTGDS antibody (N-Term) (ABIN2783248)

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGDS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PTGDS Antibody

Binding Specificity: N-Term

Sequence: MATHHTLWMG LALLGVLGDL QAAPEAQVSV QPNFQQDKFL GRWFSAGLAS

Predicted Reactivity: Dog: 86%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 80%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PTGDS. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PTGDS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 190 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTGDS

Target: PTGDS (Prostaglandin D2 Synthase (PTGDS))

Alternative Name: PTGDS

Background: PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation.The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PDS, PGD2, PGDS, PGDS2, LPGDS, L-PGDS
Protein Interaction Partner: PTGDR, HSP90AA1, KRTAP10-3, KRTAP10-7, Hk3, Hk2, ARRB2, ARR3, RARRES3, CAPN1, PTGDS, MLH1, BCAT2, ATXN1, SHBG, CACNA1A, EGFR, PTGFR, PTGER2, PTGER1,
Protein Size: 190

Molecular Weight: 21 kDa

Gene ID: 5730

NCBI Accession: NM_000954, NP_000945

UniProt: P41222