Sep 15 antibody (C-Term)

Catalog No. ABIN2783301

The Rabbit Polyclonal anti-Sep 15 antibody has been validated for WB. It is suitable to detect Sep 15 in samples from Human, Mouse, Rat, Pig, Zebrafish (Danio rerio) and Cow.

Quick Overview for Sep 15 antibody (C-Term) (ABIN2783301)

Target: Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

Reactivity: Human, Mouse, Rat, Pig, Zebrafish (Danio rerio), Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sep 15 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Sep 15 Antibody

Binding Specificity: C-Term

Sequence: LFRGLQIKYV RGSDPVLKLL DDNGNIAEEL SILKWNTDSV EEFLSEKLER

Predicted Reactivity: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against sep15. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Rat sep15

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 162 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Sep 15

Target: Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

Alternative Name: sep15

Background: This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. The exact function of this protein is not known, however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this selenoprotein in the ER, where it may play a role in protein folding.
Alias Symbols: -
Protein Interaction Partner: Rpl30,
Protein Size: 162

Molecular Weight: 17 kDa

Gene ID: 113922

NCBI Accession: NM_133297, NP_579831

UniProt: Q923V8