Sep 15 antibody (C-Term)

Catalog No. ABIN2783301

Product Details anti-Sep 15 Antibody

Target: Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Pig, Zebrafish (Danio rerio), Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sep 15 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LFRGLQIKYV RGSDPVLKLL DDNGNIAEEL SILKWNTDSV EEFLSEKLER

Predicted Reactivity: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against sep15. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Rat sep15

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 162 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Sep 15

Target: Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))

Alternative Name: sep15 (SEP15 Products)

Synonyms: 9430015P09Rik antibody, cb29 antibody, zgc:86882 antibody, BcDNA:SD16138 antibody, Dmel\\CG7484 antibody, Prise 8 antibody, Sep15 antibody, selenoprotein F antibody, CG7484 gene product from transcript CG7484-RB antibody, SELENOF antibody, Selenof antibody, selenof antibody, CG7484 antibody

Background: This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. The exact function of this protein is not known, however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this selenoprotein in the ER, where it may play a role in protein folding.
Alias Symbols: -
Protein Interaction Partner: Rpl30,
Protein Size: 162

Molecular Weight: 17 kDa

Gene ID: 113922

NCBI Accession: NM_133297, NP_579831

UniProt: Q923V8