POLG antibody (N-Term)

Catalog No. ABIN2783430

Cited in 1 publication. The Rabbit Polyclonal anti-POLG antibody (ABIN2783430) specifically detects POLG in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae and Zebrafish (Danio rerio) samples.

Quick Overview for POLG antibody (N-Term) (ABIN2783430)

Target: POLG (Polymerase (DNA Directed), gamma (POLG))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POLG Antibody

Binding Specificity: N-Term

Sequence: QDWQEQLVVG HNVSFDRAHI REQYLIQGSR MHFLDTMSMH MAISGLSSFQ

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Polg. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1216 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-POLG antibody (ABIN2783430)

Mancini, Roncaglia, Brussino, Stevanin, Lo Buono, Krmac, Maltecca, Gazzano, Bartoletti Stella, Calvaruso, Iommarini, Cagnoli, Forlani, Le Ber, Durr, Brice, Ghigo, Casari, Porcelli, Funaro, Gasparre et al.: "Genome-wide expression profiling and functional characterization of SCA28 lymphoblastoid cell lines reveal impairment in cell growth and activation of apoptotic pathways. ..." in: BMC medical genomics, Vol. 6, pp. 22, (2013) (PubMed).

Target Details for POLG

Target: POLG (Polymerase (DNA Directed), gamma (POLG))

Alternative Name: Polg

Background: Polg is involved in the replication of mitochondrial DNA.
Alias Symbols: -
Protein Size: 1216

Molecular Weight: 136 kDa

Gene ID: 85472

NCBI Accession: NM_053528, NP_445980

UniProt: Q9QYV8