NDFIP2 antibody (Middle Region)

Catalog No. ABIN2783749

This Rabbit Polyclonal antibody specifically detects NDFIP2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig, Pig and Rabbit.

Quick Overview for NDFIP2 antibody (Middle Region) (ABIN2783749)

Target: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDFIP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NDFIP2 Antibody

Binding Specificity: Middle Region

Purpose: NDFIP2 Antibody - middle region

Sequence: SFCITNTIAG RYGAICGFGL SLIKWILIVR FSDYFTGYFN GQYWLWWIFL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against NDFIP2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NDFIP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49441-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NDFIP2

Target: NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))

Alternative Name: NDFIP2

Background:

Background Information: NDFIP2 activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, NDFIP2 may control many cellular processes. NDFIP2 recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. NDFIP2 may modulate EGFR signaling.

Gene Name: Nedd4 family interacting protein 2

Alternative Symbols: N4WBP5A

Protein Name: NEDD4 family-interacting protein 2

Molecular Weight: 36kDa

Gene ID: 54602

NCBI Accession: NP_061953

UniProt: Q9NV92

Pathways: Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome