AIM2 antibody (N-Term)

Catalog No. ABIN2784209

This Rabbit Polyclonal antibody specifically detects AIM2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse and Zebrafish (Danio rerio).

Quick Overview for AIM2 antibody (N-Term) (ABIN2784209)

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Reactivity: Human, Mouse, Rat, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AIM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AIM2 Antibody

Binding Specificity: N-Term

Sequence: ESKYKEILLL TGLDNITDEE LDRFKFFLSD EFNIATGKLH TANRIQVATL

Predicted Reactivity: Horse: 100%, Human: 100%, Mouse: 79%, Rat: 79%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against AIM2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AIM2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 343 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AIM2

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Alternative Name: AIM2

Background: AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.
Alias Symbols: PYHIN4
Protein Interaction Partner: APPBP2,
Protein Size: 343

Molecular Weight: 39 kDa

Gene ID: 9447

NCBI Accession: NM_004833, NP_004824

UniProt: O14862

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome