MED25 antibody (C-Term)
Quick Overview for MED25 antibody (C-Term) (ABIN2784292)
Target
See all MED25 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- PPLLHPPPAQ SWPAQLPPRA PLPGQMLLSG GPRGPVPQPG LQPSVMEDDI
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
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Characteristics
- This is a rabbit polyclonal antibody against MED25. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of human MED25
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MED25 (Mediator Complex Subunit 25 (MED25))
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Alternative Name
- MED25
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Background
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This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2.
Alias Symbols: P78, ACID1, ARC92, BVSYS, PTOV2, CMT2B2, TCBAP0758
Protein Size: 233 -
Molecular Weight
- 25 kDa
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Gene ID
- 81857
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NCBI Accession
- NM_030973, NP_112235
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UniProt
- Q71SY5
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Pathways
- Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response
Target
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