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MED25 antibody (C-Term)

This Rabbit Polyclonal antibody specifically detects MED25 in WB and ChIP. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Pig, Horse and Rabbit.
Catalog No. ABIN2784292
$483.54
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Quick Overview for MED25 antibody (C-Term) (ABIN2784292)

Target

See all MED25 Antibodies
MED25 (Mediator Complex Subunit 25 (MED25))

Reactivity

  • 22
  • 14
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse, Rat, Cow, Dog, Pig, Horse, Rabbit

Host

  • 22
Rabbit

Clonality

  • 22
Polyclonal

Conjugate

  • 13
  • 3
  • 2
  • 2
  • 1
  • 1
This MED25 antibody is un-conjugated

Application

  • 16
  • 11
  • 8
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
  • Binding Specificity

    • 13
    • 4
    • 2
    • 1
    • 1
    • 1
    C-Term

    Sequence

    PPLLHPPPAQ SWPAQLPPRA PLPGQMLLSG GPRGPVPQPG LQPSVMEDDI

    Predicted Reactivity

    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

    Characteristics

    This is a rabbit polyclonal antibody against MED25. It was validated on Western Blot.

    Purification

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C-terminal region of human MED25
  • Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeat freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    MED25 (Mediator Complex Subunit 25 (MED25))

    Alternative Name

    MED25

    Background

    This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2.
    Alias Symbols: P78, ACID1, ARC92, BVSYS, PTOV2, CMT2B2, TCBAP0758
    Protein Size: 233

    Molecular Weight

    25 kDa

    Gene ID

    81857

    NCBI Accession

    NM_030973, NP_112235

    UniProt

    Q71SY5

    Pathways

    Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response
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