TNFRSF12A antibody (N-Term)

Catalog No. ABIN2784518

Product Details anti-TNFRSF12A Antibody

Target: TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF12A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MASAWPRSLP QILVLGFGLV LMRAAAGEQA PGTSPCSSGS SWSADLDKCM

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Tnfrsf12a. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 129 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TNFRSF12A

Target: TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))

Alternative Name: Tnfrsf12a (TNFRSF12A Products)

Synonyms: CD266 antibody, FN14 antibody, TWEAKR antibody, AI255180 antibody, C87282 antibody, Fn14 antibody, HPIP antibody, TWEAK-R antibody, TweakR antibody, TNF receptor superfamily member 12A antibody, tumor necrosis factor receptor superfamily, member 12a antibody, TNFRSF12A antibody, Tnfrsf12a antibody

Background: Tnfrsf12a is a receptor for TNFSF12/TWEAK By similarity and weak inducer of apoptosis in some cell types. Tnfrsf12a promotes angiogenesis and the proliferation of endothelial cells and may modulate cellular adhesion to matrix proteins.
Alias Symbols: AI255180, C87282, Fn14, HPIP, TWEAK-R, TweakR
Protein Interaction Partner: TRAF5, TRAF3, TRAF2, TRAF1,
Protein Size: 129

Molecular Weight: 14 kDa

Gene ID: 27279

NCBI Accession: NM_013749, NP_038777

UniProt: Q9CR75

Pathways: Apoptosis, Regulation of Cell Size