CRYM antibody (Middle Region)

Catalog No. ABIN2784722

The Rabbit Polyclonal anti-CRYM antibody is suitable to detect CRYM in samples from Human, Mouse, Rat, Cow, Dog, Goat, Horse, Rabbit and Guinea Pig. It has been validated for WB.

Quick Overview for CRYM antibody (Middle Region) (ABIN2784722)

Target: CRYM (Crystallin, mu (CRYM))

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRYM antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRYM Antibody

Binding Specificity: Middle Region

Purpose: CRYM Antibody - middle region

Sequence: AHINAVGASR PDWRELDDEL MKEAVLYVDS QEAALKESGD VLLSGAEIFA

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CRYM. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CRYM

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51982-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRYM

Target: CRYM (Crystallin, mu (CRYM))

Alternative Name: CRYM

Background:

Background Information: Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene.

Gene Name: Crystallin, mu

Alternative Symbols: THBP, DFNA40

Protein Name: Thiomorpholine-carboxylate dehydrogenase

Molecular Weight: 30kDa

Gene ID: 1428

NCBI Accession: NP_001014444

UniProt: D5MNX0

Pathways: Hormone Transport, Sensory Perception of Sound