eIF4EBP1 antibody (N-Term)

Catalog No. ABIN2784742

This Rabbit Polyclonal antibody specifically detects eIF4EBP1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Rabbit, Guinea Pig, Horse and Goat.

Quick Overview for eIF4EBP1 antibody (N-Term) (ABIN2784742)

Target: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Rabbit, Guinea Pig, Horse, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This eIF4EBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-eIF4EBP1 Antibody

Binding Specificity: N-Term

Sequence: ALGDGVQLPP GDYSTTPGGT LFSTTPGGTR IIYDRKFLME CRNSPVAKTP

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against Eif4ebp1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 117 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for eIF4EBP1

Target: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Alternative Name: Eif4ebp1

Background: Eif4ebp1 regulates eIF4E activity by preventing its assembly into the eIF4F complex. It mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Alias Symbols: 4e-bp1, AA959816, PHAS-I
Protein Interaction Partner: RAD23B, Mapk1, Ubc, Eif4e,
Protein Size: 117

Molecular Weight: 12 kDa

Gene ID: 13685

NCBI Accession: NM_007918, NP_031944

UniProt: Q60876

Pathways: MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size, BCR Signaling