SPON2 antibody (N-Term)

Catalog No. ABIN2784889

The Rabbit Polyclonal anti-SPON2 antibody is suitable to detect SPON2 in samples from Human, Mouse, Rat, Cow, Guinea Pig, Horse and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for SPON2 antibody (N-Term) (ABIN2784889)

Target: SPON2 (Spondin 2 (SPON2))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPON2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPON2 Antibody

Binding Specificity: N-Term

Purpose: SPON2 Antibody - N-terminal region

Sequence: CSARAPAKYS ITFTGKWSQT AFPKQYPLFR PPAQWSSLLG AAHSSDYSMW

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SPON2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SPON2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52335-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPON2

Target: SPON2 (Spondin 2 (SPON2))

Alternative Name: SPON2

Background:

Background Information: SPON2 is a cell adhesion protein that promote adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. It is essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens.

Gene Name: Spondin 2, extracellular matrix protein

Alternative Symbols: DIL1, DIL-1, MINDIN, M-SPONDIN

Protein Name: Spondin-2

Molecular Weight: 36kDa

Gene ID: 10417

NCBI Accession: NP_036577

UniProt: Q9BUD6