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AKR1C2 antibody (N-Term)

AKR1C2 Reactivity: Human, Rat, Mouse, Cow, Horse, Rabbit, Dog, Guinea Pig, Sheep WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2785422
  • Target See all AKR1C2 Antibodies
    AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
    Binding Specificity
    • 10
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Rat, Mouse, Cow, Horse, Rabbit, Dog, Guinea Pig, Sheep
    Host
    • 40
    • 7
    Rabbit
    Clonality
    • 43
    • 4
    Polyclonal
    Conjugate
    • 27
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKR1C2 antibody is un-conjugated
    Application
    • 37
    • 26
    • 17
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LEAVKLAIEA GFHHIDSAHV YNNEEQVGLA IRSKIADGSV KREDIFYTSK
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 86%
    Characteristics
    This is a rabbit polyclonal antibody against AKR1C2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1C2
    Top Product
    Discover our top product AKR1C2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 323 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
    Alternative Name
    AKR1C2 (AKR1C2 Products)
    Synonyms
    AKR1C-pseudo antibody, BABP antibody, DD antibody, DD2 antibody, DDH2 antibody, HAKRD antibody, HBAB antibody, MCDR2 antibody, SRXY8 antibody, Akr1c21 antibody, aldo-keto reductase family 1 member C2 antibody, aldo-keto reductase family 1, member C2 antibody, AKR1C2 antibody, Akr1c2 antibody
    Background
    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
    Alias Symbols: AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8
    Protein Interaction Partner: UBC, AKR1C2,
    Protein Size: 323
    Molecular Weight
    37 kDa
    Gene ID
    1646
    NCBI Accession
    NM_205845, NP_995317
    UniProt
    P52895
    Pathways
    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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