AKR1C2 antibody (N-Term)
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- Target See all AKR1C2 Antibodies
- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
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Binding Specificity
- N-Term
- Reactivity
- Human, Rat, Mouse, Cow, Horse, Rabbit, Dog, Guinea Pig, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This AKR1C2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LEAVKLAIEA GFHHIDSAHV YNNEEQVGLA IRSKIADGSV KREDIFYTSK
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 86%
- Characteristics
- This is a rabbit polyclonal antibody against AKR1C2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1C2
- Top Product
- Discover our top product AKR1C2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 323 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
- Alternative Name
- AKR1C2 (AKR1C2 Products)
- Synonyms
- AKR1C-pseudo antibody, BABP antibody, DD antibody, DD2 antibody, DDH2 antibody, HAKRD antibody, HBAB antibody, MCDR2 antibody, SRXY8 antibody, Akr1c21 antibody, aldo-keto reductase family 1 member C2 antibody, aldo-keto reductase family 1, member C2 antibody, AKR1C2 antibody, Akr1c2 antibody
- Background
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8
Protein Interaction Partner: UBC, AKR1C2,
Protein Size: 323 - Molecular Weight
- 37 kDa
- Gene ID
- 1646
- NCBI Accession
- NM_205845, NP_995317
- UniProt
- P52895
- Pathways
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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