ERCC5 antibody (N-Term)

Catalog No. ABIN2785634

The Rabbit Polyclonal anti-ERCC5 antibody (ABIN2785634) specifically detects ERCC5 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Guinea Pig samples.

Quick Overview for ERCC5 antibody (N-Term) (ABIN2785634)

Target: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERCC5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ERCC5 Antibody

Binding Specificity: N-Term

Purpose: ERCC5 Antibody - N-terminal region

Sequence: NPQAIDIESE DFSSLPPEVK HEILTDMKEF TKRRRTLFEA MPEESDDFSQ

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ERCC5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54287-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ERCC5

Target: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Alternative Name: ERCC5

Background:

Background Information: Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Excision repair cross-complementing rodent repair deficiency, complementation group 5

Alternative Symbols: XPG, UVDR, XPGC, COFS3, ERCM2, ERCC5-201

Protein Name: DNA repair protein complementing XP-G cells

Molecular Weight: 133kDa

Gene ID: 2073

NCBI Accession: NP_000114

UniProt: P28715

Pathways: DNA Damage Repair