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TMOD3 antibody (Middle Region)

TMOD3 Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2786043
  • Target See all TMOD3 Antibodies
    TMOD3 (Tropomodulin 3 (TMOD3))
    Binding Specificity
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 15
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Guinea Pig, Zebrafish (Danio rerio)
    Host
    • 11
    • 5
    Rabbit
    Clonality
    • 14
    • 2
    Polyclonal
    Conjugate
    • 16
    This TMOD3 antibody is un-conjugated
    Application
    • 14
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    ITNTKFCNIM GSSNGVDQEH FSNVVKGEKI LPVFDEPPNP TNVEESLKRT
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    Characteristics
    This is a rabbit polyclonal antibody against TMOD3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human TMOD3
    Top Product
    Discover our top product TMOD3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 352 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TMOD3 (Tropomodulin 3 (TMOD3))
    Alternative Name
    TMOD3 (TMOD3 Products)
    Synonyms
    TMOD3 antibody, tropomodulin-3 antibody, UTMOD antibody, MGC53545 antibody, U-Tmod antibody, tropomodulin 3 antibody, tropomodulin 3 S homeolog antibody, TMOD3 antibody, Tmod3 antibody, tmod3.S antibody, tmod3 antibody
    Background
    TMOD3 belongs to the tropomodulin family. It blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway.
    Alias Symbols: UTMOD
    Protein Interaction Partner: UBC, PABPC1, YWHAE, PSMD9, PPP1CA, DHX15, PAN2, CSNK2A1, HNRNPUL2, PPIL3, AHCYL1, SULT1A1, PSMC4, PSMB7, NPC1, ATP6V1B1, LRRK2, FBXO25, ISG15, ARRB2, ARRB1, ELAVL1, SUMO2, DUSP23, TNFSF11, MAP1LC3B, Poc1b, Tubgcp3, Sass6, Trim69, Stag2, Pafah1b1, Erh, Cdk
    Protein Size: 352
    Molecular Weight
    39 kDa
    Gene ID
    29766
    NCBI Accession
    NM_014547, NP_055362
    UniProt
    Q9NYL9
    Pathways
    Regulation of Actin Filament Polymerization
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