MAP3K11 antibody (Middle Region)

Catalog No. ABIN2786655

The Rabbit Polyclonal anti-MAP3K11 antibody has been validated for WB. It is suitable to detect MAP3K11 in samples from Human, Mouse, Rat, Cow, Guinea Pig, Horse and Rabbit.

Quick Overview for MAP3K11 antibody (Middle Region) (ABIN2786655)

Target: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAP3K11 Antibody

Binding Specificity: Middle Region

Sequence: PVGQRSAKSP RREEEPRGGT VSPPPGTSRS APGTPGTPRS PPLGLISRPR

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MAP3K11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAP3K11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 847 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAP3K11

Target: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Alternative Name: MAP3K11

Background: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK sig
Alias Symbols: MGC17114, MLK-3, MLK3, PTK1, SPRK, MEKK11
Protein Interaction Partner: STUB1, UBC, HSP90AA1, HSPA4, APP, CDC37, MAP2K7, HSP90AB1, PIN1, GSK3B, GSK3A, EPS8, MAPK8IP1, TRAF6, MAP3K11, CBL, MAP4K2, TRIM5, CLEC4G, TRAF2, COPS5, SH3RF1, MAPK8IP3, MAPK8IP2, KIF3A, IKBKB, RAC1, MAP4K1, CHUK, MAP3K12, RHOG, AKT1, CDC42, MAP2K4, DLG4
Protein Size: 847

Molecular Weight: 93 kDa

Gene ID: 4296

NCBI Accession: NM_002419, NP_002410

UniProt: Q16584

Pathways: MAPK Signaling, Interferon-gamma Pathway