PIM1 antibody (N-Term)

Catalog No. ABIN503951

The Rabbit Polyclonal anti-PIM1 antibody is suitable to detect PIM1 in samples from Human, Mouse, Rat, Horse, Sheep, Cow, Dog, Rabbit and Guinea Pig. It has been validated for WB.

Quick Overview for PIM1 antibody (N-Term) (ABIN503951)

Target: PIM1 (Pim-1 Oncogene (PIM1))

Reactivity: Human, Mouse, Rat, Horse, Sheep, Cow, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PIM1 Antibody

Binding Specificity: N-Term

Sequence: MLLSKINSLA HLRAAPCNDL HATKLAPGKE KEPLESQYQV GPLLGSGGFG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against PIM1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PIM1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 313 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIM1

Target: PIM1 (Pim-1 Oncogene (PIM1))

Alternative Name: PIM1

Background: PIM1 may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. Isoform 2 promotes the G1/S transition of the cell cycle via up-regulation of CDK2 activity and phosphorylation of CDKN1B, resulting in enhanced nuclear export and
Alias Symbols: PIM
Protein Interaction Partner: FXR2, NHLH1, FH, BEND7, HEXIM2, BANP, TFPT, ZBTB1, UBC, APP, MARK3, HSP90AA1, HSPA4, PIM1, MDM2, ELAVL1, FZR1, SKP2, PPP2R5E, PPP2R4, PPP2CA, PIN1, CDC34, CDC20, ABCB1, HIST2H3C, MYC, MAX, SNX6, CBX1, CBX3, BAD, HIST3H3, SND1, PTPRO, NFATC1, SHMT1, EPHA3,
Protein Size: 404

Molecular Weight: 45 kDa

Gene ID: 5292

NCBI Accession: NM_002648, NP_002639

Pathways: Glycosaminoglycan Metabolic Process