CRBN antibody (N-Term)

Catalog No. ABIN2786956

Product Details anti-CRBN Antibody

Target: CRBN (Cereblon (CRBN))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRBN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DQDSKEAKKP NIINFDTSLP TSHTYLGADM EEFHGRTLHD DDSCQVIPVL

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CRBN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CRBN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 442 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRBN

Target: CRBN (Cereblon (CRBN))

Alternative Name: CRBN (CRBN Products)

Background: This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutatio
Alias Symbols: DKFZp781K0715, MGC27358, MRT2A, MRT2
Protein Interaction Partner: PAK7, RBPMS, MEIS2, DDB1, IKZF3, IKZF1, SUV39H1, KDM1A, UBC, COPS4, COPS6, COPS3, PSMB4, PSMA2, COPS5, CUL4A, PRKAA1, RBX1,
Protein Size: 442

Molecular Weight: 50 kDa

Gene ID: 51185

NCBI Accession: NM_016302, NP_057386

UniProt: Q96SW2