P4HTM antibody (Middle Region)

Catalog No. ABIN2787377

This Rabbit Polyclonal antibody specifically detects P4HTM in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse, Cow, Dog, Rabbit, Guinea Pig and Pig.

Quick Overview for P4HTM antibody (Middle Region) (ABIN2787377)

Target: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Rabbit, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P4HTM antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-P4HTM Antibody

Binding Specificity: Middle Region

Sequence: RLGNGWWMTP ESIQEMYAAI KADPDGDGVL SLQEFSNMDL RDFHKYMRSH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PH-4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PH-4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 502 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for P4HTM

Target: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Alternative Name: PH-4

Background: The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and m
Alias Symbols: P4H-TM, PH4, PH-4, PHD4, EGLN4, HIFPH4
Protein Interaction Partner: GLP1R, PDIA2, nef, UBC, CD1D,
Protein Size: 502

Molecular Weight: 57 kDa

Gene ID: 54681

NCBI Accession: NM_177939, NP_808808

UniProt: Q9NXG6