SUMO3 antibody (Middle Region)

Catalog No. ABIN2787608

This Rabbit Polyclonal antibody specifically detects SUMO3 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for SUMO3 antibody (Middle Region) (ABIN2787608)

Target: SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUMO3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SUMO3 Antibody

Binding Specificity: Middle Region

Sequence: MRQIRFRFDG QPINETDTPA QLEMEDEDTI DVFQQQTGGV PESSLAGHSF

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SUMO3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SUMO3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 103 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SUMO3

Target: SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))

Alternative Name: SUMO3

Background: SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability.SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 [PubMed 12383504]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: SMT3A, SMT3H1, SUMO-3, Smt3B
Protein Interaction Partner: PML, USPL1, UBC, HIF1A, ESRRA, EP300, SENP1, USP25, SENP5, SENP2, TP53, SP100, RANGAP1, RGPD8, SUMO3, TRA2B, SDHA, GNB2, GNB1, GART, GAPDH, XRCC6, FLNA, FEN1, FASN, FBL, ENO1, EMD, EIF4A2, EIF4A1, EIF2S1, EEF2, EEF1G, EEF1D, EEF1A1, DNMT1, DYNC1H1, DHX15,
Protein Size: 103

Molecular Weight: 12 kDa

Gene ID: 6612

NCBI Accession: NM_006936, NP_008867

UniProt: P55854