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ERK2 antibody (Middle Region)

MAPK1 Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Horse, Zebrafish (Danio rerio), Guinea Pig, Goat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787871
  • Target See all ERK2 (MAPK1) Antibodies
    ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))
    Binding Specificity
    • 16
    • 11
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 132
    • 70
    • 67
    • 13
    • 9
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    Human, Mouse, Rat, Dog, Cow, Rabbit, Horse, Zebrafish (Danio rerio), Guinea Pig, Goat
    Host
    • 97
    • 33
    • 4
    • 3
    • 1
    Rabbit
    Clonality
    • 88
    • 51
    Polyclonal
    Conjugate
    • 87
    • 11
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This ERK2 antibody is un-conjugated
    Application
    • 101
    • 65
    • 40
    • 29
    • 24
    • 23
    • 13
    • 9
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    RDLKPSNLLL NTTCDLKICD FGLARVADPD HDHTGFLTEY VATRWYRAPE
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against MAPK1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human MAPK1
    Top Product
    Discover our top product MAPK1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 360 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))
    Alternative Name
    MAPK1 (MAPK1 Products)
    Synonyms
    ERK-1 antibody, ERK1 antibody, ERT2 antibody, HS44KDAP antibody, HUMKER1A antibody, P44ERK1 antibody, P44MAPK antibody, PRKM3 antibody, p44-ERK1 antibody, p44-MAPK antibody, Erk-1 antibody, Erk1 antibody, Ert2 antibody, Esrk1 antibody, Mnk1 antibody, Mtap2k antibody, Prkm3 antibody, p44 antibody, p44erk1 antibody, p44mapk antibody, ERK antibody, ERK2 antibody, ERT1 antibody, MAPK2 antibody, P42MAPK antibody, PRKM1 antibody, PRKM2 antibody, p38 antibody, p40 antibody, p41 antibody, p41mapk antibody, 9030612K14Rik antibody, AA407128 antibody, AU018647 antibody, C78273 antibody, Erk2 antibody, Prkm1 antibody, p42mapk antibody, zERK2 antibody, MAPK1 antibody, Xp42 antibody, erk antibody, erk2 antibody, ert1 antibody, mapk antibody, mapk1b antibody, mapk2 antibody, mpk1 antibody, prkm1 antibody, prkm2 antibody, mapk1 antibody, mapk1a antibody, xp42 antibody, ATMPK1 antibody, F14N23.9 antibody, F14N23_9 antibody, MITOGEN-ACTIVATED PROTEIN KINASE antibody, mitogen-activated protein kinase 1 antibody, MNK1 antibody, ATMPK2 antibody, MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2 antibody, T30E16.13 antibody, T30E16_13 antibody, mitogen-activated protein kinase homolog 2 antibody, mitogen-activated protein kinase 3 antibody, mitogen-activated protein kinase 1 antibody, mitogen activated protein kinase 1 antibody, mitogen-activated protein kinase 1 L homeolog antibody, mitogen-activated protein kinase 1 S homeolog antibody, mitogen activated protein kinase 3 antibody, mitogen-activated protein kinase homolog 2 antibody, MAPK3 antibody, Mapk3 antibody, MAPK1 antibody, Mapk1 antibody, mapk1 antibody, mapk1.L antibody, mapk1.S antibody, PfMAP1 antibody, MPK1 antibody, PVX_084965 antibody, LOC9328617 antibody, Tsp_01601 antibody, MPK2 antibody
    Background
    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
    Alias Symbols: ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
    Protein Interaction Partner: Eif4ebp1, ATF2, RPS6KA3, RAF1, PTGDR, MAP2K6, MAP2K1, MAPK3, HDAC6, TP53, NEDD8, DGCR8, HMGB1, NAV1, PDCD6IP, CEP350, MAPK12, RPS6KA2, MAPK1, PDE4D, MBP, KRAS, SQSTM1, CUEDC2, GAB2, BRAF, RPS6KA1, MAP2K4, MAP2K2, ELK1, NOXA1, TIAL1, GADD45A, MAP3K10, SMAD
    Protein Size: 360
    Molecular Weight
    41 kDa
    Gene ID
    5594
    NCBI Accession
    NM_138957, NP_620407
    UniProt
    P28482
    Pathways
    MAPK Signaling, RTK Signaling, Apoptosis, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteins
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