ULK3 antibody (Middle Region)

Catalog No. ABIN2787898

The Rabbit Polyclonal anti-ULK3 antibody is suitable to detect ULK3 in samples from Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Rabbit and Horse. It has been validated for WB.

Quick Overview for ULK3 antibody (Middle Region) (ABIN2787898)

Target: ULK3 (Unc-51-Like Kinase 3 (ULK3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ULK3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ULK3 Antibody

Binding Specificity: Middle Region

Purpose: ULK3 Antibody - middle region

Sequence: LGRATALVVQ AVKKDQEGDS AAALSLYCKA LDFFVPALHY EVDAQRKEAI

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ULK3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ULK3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58971-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ULK3

Target: ULK3 (Unc-51-Like Kinase 3 (ULK3))

Alternative Name: ULK3

Background:

Background Information: ULK3 is the serine/threonine protein kinase which enhances GLI1 and GLI2 transcriptional activity and consequently positively regulates GLI-dependent SHH signaling. ULK3 may exert this function by promoting GLI1 nuclear localization. ULK3 phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently.

Gene Name: Unc-51-like kinase 3 (C. elegans)

Alternative Symbols: DKFZp434C131, FLJ90566

Protein Name: Serine/threonine-protein kinase ULK3

Molecular Weight: 53kDa

Gene ID: 25989

NCBI Accession: NP_001092906

UniProt: Q6PHR2