ERC1 antibody (C-Term)

Catalog No. ABIN2788091

The Rabbit Polyclonal anti-ERC1 antibody has been validated for WB. It is suitable to detect ERC1 in samples from Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for ERC1 antibody (C-Term) (ABIN2788091)

Target: ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ERC1 Antibody

Binding Specificity: C-Term

Sequence: KLMADNYEDD HFKSSHSNQT NHKPSPDQII QPLLELDQNR SKLKLYIGHL

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against ERC1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ERC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1116 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ERC1

Target: ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1))

Alternative Name: ERC1

Background: The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10,12)(q11,p13). Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: Cast2, ELKS, FLJ31750, KIAA1081, MGC12974, RAB6IP2
Protein Interaction Partner: UBC, LATS2, CDK20, CDK19, MAPK4, STK4, PAN2, MYC, ATP6V0D1, NCBP1, APP, ERC2, WDR4, CUL3, IKBKG, NFKBIA, IKBKB, CHUK, SH3KBP1, ITSN2, RAD23A, YWHAG, MAP3K7, XIAP, KBTBD7, RAB6B, PPFIA1, RIMS1, ERC1, RAB6A, TWF2,
Protein Size: 1116

Molecular Weight: 128 kDa

Gene ID: 23085

NCBI Accession: NM_178040, NP_829884

UniProt: Q8IUD2

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection