ERC1 antibody (N-Term)

Catalog No. ABIN6256850

This Rabbit Polyclonal antibody specifically detects ERC1 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ERC1 antibody (N-Term) (ABIN6256850)

Target: ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ERC1 Antibody

Binding Specificity: N-Term

Purpose: RB6I2 Antibody

Specificity: RB6I2 Antibody detects endogenous levels of total RB6I2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RB6I2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ERC1

Target: ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1))

Alternative Name: RB6I2

Background:

Description: Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport.

Gene: ERC1

Gene ID: 23085

UniProt: Q8IUD2

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection