ERC1 antibody

Catalog No. ABIN7230966

This Rabbit Polyclonal antibody specifically detects ERC1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ERC1 antibody (ABIN7230966)

Target: ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ERC1 Antibody

Purpose: Rabbit Anti-RB6I2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RB6I2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RB6I2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ERC1

Target: ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1))

Alternative Name: RB6I2

Background: ELKS/Rab6-interacting/CAST family member 1, ERC-1, Rab6-interacting protein 2The protein encoded by ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1) is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10,12)(q11,p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. ERC1 is a Protein Coding gene. Diseases associated with ERC1 include Differentiated Thyroid Carcinoma and Distal Monosomy 12P. Among its related pathways are NF-kappa B signaling pathway and Cytoskeletal Signaling.

Molecular Weight: 122kD

Gene ID: 23085

UniProt: Q8IUD2

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection