Calnexin antibody (Middle Region)

Catalog No. ABIN2788199

Product Details anti-Calnexin Antibody

Target: Calnexin (CANX)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse, Goat, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calnexin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LVDQSVVNSG NLLNDMTPPV NPSREIEDPE DRKPEDWDER PKIPDPEAVK

Predicted Reactivity: Cow: 100%, Dog: 93%, Goat: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 80%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CANX. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CANX

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 592 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Calnexin

Target: Calnexin (CANX)

Alternative Name: CANX (CANX Products)

Synonyms: CNX antibody, IP90 antibody, P90 antibody, 1110069N15Rik antibody, AI988026 antibody, Cnx antibody, D11Ertd153e antibody, canx antibody, clgn antibody, clnx antibody, cnx antibody, PP90 antibody, zgc:63524 antibody, wu:fe06b12 antibody, CANX antibody, calnexin antibody, CalNeXin antibody, calnexin L homeolog antibody, CANX antibody, Canx antibody, cnx-1 antibody, canx.L antibody, canx antibody, LOC100283947 antibody

Background: This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
Alias Symbols: CNX, FLJ26570, IP90, P90
Protein Interaction Partner: ERLIN2, HUWE1, UBC, TRAF6, SUMO2, TOR1A, STAU1, MDM2, LGR4, WWOX, NPHS1, RPA3, RPA2, RPA1, SUZ12, RNF2, BMI1, FBXO6, PTGIR, ADRB2, PDIA3, CLN5, YIPF3, SMURF2, env, PGRMC1, BCAP31, UBL4A, SERPINA1, MTNR1A, CSNK2A1, ATF2, CFTR, VCP, PKD2, LDLR, ASGR1, KCNH2
Protein Size: 592

Molecular Weight: 65 kDa

Gene ID: 821

NCBI Accession: NM_001746, NP_001737

UniProt: P27824

Pathways: MAPK Signaling, Thyroid Hormone Synthesis