Adenosine A3 Receptor antibody (C-Term)

Catalog No. ABIN2788279

Product Details anti-Adenosine A3 Receptor Antibody

Target: Adenosine A3 Receptor (ADORA3)

Binding Specificity: C-Term

Reactivity: Human, Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenosine A3 Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DFTELIVTDD KGTLANDFWS GKDLSGNKTR SCKAPKVVRK ADRSRTSILI

Predicted Reactivity: Cow: 79%, Human: 100%, Pig: 79%

Characteristics: This is a rabbit polyclonal antibody against ADORA3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 347 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Adenosine A3 Receptor

Target: Adenosine A3 Receptor (ADORA3)

Alternative Name: ADORA3 (ADORA3 Products)

Background: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death.
Alias Symbols: A3AR, AD026, bA552M11.5, RP11-552M11.7
Protein Interaction Partner: YWHAQ, YWHAZ,
Protein Size: 347

Molecular Weight: 39 kDa

Gene ID: 140

NCBI Accession: NM_020683, NP_065734

UniProt: P33765

Pathways: Hormone Transport, cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process