COL4a6 antibody (Middle Region)

Catalog No. ABIN2788304

Product Details anti-COL4a6 Antibody

Target: COL4a6 (Collagen, Type IV, alpha 6 (COL4a6))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL4a6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GIKGKSGLPG APGFPGISGH PGKKGTRGKK GPPGSIVKKG LPGLKGLPGN

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against COL4A6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COL4A6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1691 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COL4a6

Target: COL4a6 (Collagen, Type IV, alpha 6 (COL4a6))

Alternative Name: COL4A6 (COL4a6 Products)

Synonyms: CXDELq22.3 antibody, DELXq22.3 antibody, BB116301 antibody, collagen type IV alpha 6 chain antibody, collagen, type IV, alpha 6 antibody, COL4A6 antibody, Col4a6 antibody, col4a6 antibody

Background: This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene.
Alias Symbols: MGC88184, DELXq22.3, CXDELq22.3
Protein Interaction Partner: APP, VHL, HABP2, MATN2, SERPINE2, OSM, FBLN2, FN1, DCN, CD93, MMP9,
Protein Size: 1691

Molecular Weight: 161 kDa

Gene ID: 1288

NCBI Accession: NM_001847, NP_001838

UniProt: Q14031