COL9A1 antibody (N-Term)

Catalog No. ABIN2788309

Product Details anti-COL9A1 Antibody

Target: COL9A1 (Collagen, Type IX, alpha 1 (COL9A1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL9A1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GADGLTGPDG SPGSIGSKGQ KGEPGVPGSR GFPGRGIPGP PGPPGTAGLP

Predicted Reactivity: Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against COL9A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human COL9A1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 678 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COL9A1

Target: COL9A1 (Collagen, Type IX, alpha 1 (COL9A1))

Alternative Name: COL9A1 (COL9A1 Products)

Synonyms: cb339 antibody, sb:cb339 antibody, zgc:85892 antibody, wu:fa12a12 antibody, wu:fa12d02 antibody, wu:fc22c08 antibody, wu:fc38d08 antibody, edm6 antibody, MGC82441 antibody, DJ149L1.1.2 antibody, EDM6 antibody, MED antibody, STL4 antibody, Col9a-1 antibody, collagen, type IX, alpha 1b antibody, collagen, type IX, alpha 1 L homeolog antibody, collagen type IX alpha 1 chain antibody, collagen, type IX, alpha 1 antibody, collagen alpha-1(IX) chain antibody, col9a1b antibody, col9a1.L antibody, COL9A1 antibody, Col9a1 antibody, LOC101102992 antibody

Background: This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20 % ) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.
Alias Symbols: DJ149L1.1.2, EDM6, FLJ40263, MED, STL4
Protein Interaction Partner: COMP, MAG, COL2A1,
Protein Size: 678

Molecular Weight: 62 kDa

Gene ID: 1297

NCBI Accession: NM_078485, NP_511040

UniProt: A6NEQ6