CD55 antibody (Middle Region)

Catalog No. ABIN2788355

The Rabbit Polyclonal anti-CD55 antibody is suitable to detect CD55 in samples from Human, Dog and Horse. It has been validated for WB.

Quick Overview for CD55 antibody (Middle Region) (ABIN2788355)

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivity: Human, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD55 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD55 Antibody

Binding Specificity: Middle Region

Purpose: CD55 Antibody - middle region

Sequence: PGYRREPSLS PKLTCLQNLK WSTAVEFCKK KSCPNPGEIR NGQIDVPGGI

Predicted Reactivity: Dog: 79%, Horse: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CD55. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CD55

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60155-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Alternative Name: CD55

Background:

Background Information: This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF), binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels.

Gene Name: CD55 Molecule, decay accelerating factor for complement (Cromer blood group)

Alternative Symbols: CR, TC, DAF, CROM, CHAPLE

Protein Name: Complement decay-accelerating factor

Molecular Weight: 41kDa

Gene ID: 1604

NCBI Accession: NP_000565

UniProt: P08174

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity