CAPNS2 antibody (N-Term)

Catalog No. ABIN2788439

The Rabbit Polyclonal anti-CAPNS2 antibody is suitable to detect CAPNS2 in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Pig, Rabbit and Sheep. It has been validated for WB.

Quick Overview for CAPNS2 antibody (N-Term) (ABIN2788439)

Target: CAPNS2 (Calpain, Small Subunit 2 (CAPNS2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPNS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CAPNS2 Antibody

Binding Specificity: N-Term

Purpose: CAPNS2 Antibody - N-terminal region

Sequence: GRNIGGIVGG IVNFISEAAA AQYTPEPPPT QQHFTSVEAS ESEEVRRFRQ

Predicted Reactivity: Cow: 75%, Dog: 75%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 93%, Rat: 75%, Sheep: 82%

Characteristics: This is a rabbit polyclonal antibody against CAPNS2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CAPNS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60408-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CAPNS2

Target: CAPNS2 (Calpain, Small Subunit 2 (CAPNS2))

Alternative Name: CAPNS2

Background:

Targeted Subunit: 2

Background Information: CAPNS2 is a calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.

Gene Name: Calpain, small subunit 2

Alternative Symbols: CSS2

Protein Name: Calpain small subunit 2

Molecular Weight: 28kDa

Gene ID: 84290

NCBI Accession: NP_115706

UniProt: Q96L46