CAPNL1 antibody (Middle Region)

Catalog No. ABIN2788625

This Rabbit Polyclonal antibody specifically detects CAPNL1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Goat, Horse, Rabbit, Sheep, Zebrafish (Danio rerio) and Pig.

Quick Overview for CAPNL1 antibody (Middle Region) (ABIN2788625)

Target: CAPNL1 (Calpain 1, Large Subunit (CAPNL1))

Reactivity: Human, Mouse, Rat, Cow, Goat, Horse, Rabbit, Sheep, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPNL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CAPNL1 Antibody

Binding Specificity: Middle Region

Purpose: CAPN1 Antibody - middle region

Sequence: EVEWTGAWSD SSSEWNNVDP YERDQLRVKM EDGEFWMSFR DFMREFTRLE

Predicted Reactivity: Cow: 79%, Goat: 79%, Horse: 93%, Human: 100%, Mouse: 80%, Pig: 86%, Rabbit: 79%, Rat: 83%, Sheep: 79%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against CAPN1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CAPN1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP60936-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CAPNL1

Target: CAPNL1 (Calpain 1, Large Subunit (CAPNL1))

Alternative Name: CAPN1

Background:

Background Information: The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.

Gene Name: Calpain 1, (mu/I) large subunit

Alternative Symbols: CANP, muCL, CANP1, SPG76, CANPL1, muCANP

Protein Name: Calpain-1 catalytic subunit

Molecular Weight: 82kDa

Gene ID: 823

NCBI Accession: NP_005177

UniProt: P07384

Pathways: Apoptosis