SOD1 antibody (C-Term)

Catalog No. ABIN2788679

The Rabbit Polyclonal anti-SOD1 antibody (ABIN2788679) specifically detects SOD1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Rabbit, Sheep, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio) and Goat samples.

Quick Overview for SOD1 antibody (C-Term) (ABIN2788679)

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Sheep, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio), Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SOD1 Antibody

Binding Specificity: C-Term

Purpose: SOD1 Antibody - C-terminal region

Sequence: DVSIEDSVIS LSGDHCIIGR TLVVHEKADD LGKGGNEEST KTGNAGSRLA

Predicted Reactivity: Cow: 100%, Dog: 86%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against SOD1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SOD1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61114-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOD1

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Alternative Name: SOD1

Background:

Background Information: SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in its gene have been implicated as causes of familial amyotrophic lateral sclerosis.

Alternative Symbols: ALS, SOD, ALS1, IPOA, STAHP, hSod1, HEL-S-44, homodimer

Protein Name: Superoxide dismutase [Cu-Zn]

Molecular Weight: 16 kDa

Gene ID: 6647

NCBI Accession: NP_000445

UniProt: P00441

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis