ERK2 antibody (C-Term)

Catalog No. ABIN2788693

The Rabbit Polyclonal anti-ERK2 antibody (ABIN2788693) specifically detects ERK2 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Rabbit, Zebrafish (Danio rerio), Horse, Pig, Guinea Pig and Goat samples.

Quick Overview for ERK2 antibody (C-Term) (ABIN2788693)

Target: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Zebrafish (Danio rerio), Horse, Pig, Guinea Pig, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERK2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ERK2 Antibody

Binding Specificity: C-Term

Sequence: EVEQALAHPY LEQYYDPSDE PIAEAPFKFD MELDDLPKEK LKELIFEETA

Predicted Reactivity: Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 93%, Horse: 93%, Human: 93%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Mapk1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Mapk1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ERK2

Target: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Alternative Name: Mapk1

Background: Mapk1 is a serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway.
Alias Symbols: 9030612K14Rik, AA407128, AU018647, C78273, ERK, Erk2, MAPK2, PRKM2, Prkm1, p41mapk, p42mapk
Protein Interaction Partner: nos-3, Mapk6, Mapk3, Eed, Atf2, BCL2L1, Metap2, Pxn, Mbp, Fert2, Crk, Vrk3, Dusp3, Elk1, Eif4ebp2, Eif4ebp1, Dusp2, Capn2, Sqstm1, Stat1, Itgb5, Mdk, vif, Grin2b, Grin1, Cttn, Pea15b, Pea15a, Blnk, Pcyt1a, Top2a, TP53, KLF11, Sos1, Irx2, Dync1i1, Rps6ka3,
Protein Size: 358

Molecular Weight: 41 kDa

Gene ID: 26413

NCBI Accession: NM_011949, NP_036079

UniProt: P63085

Pathways: MAPK Signaling, RTK Signaling, Apoptosis, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteins