NUP153 antibody (C-Term)

Catalog No. ABIN2788808

Product Details anti-NUP153 Antibody

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Dog, Pig, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP153 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PKCQPVFSFG NSEQTKDENS SKSTFSFSMT KPSEKESEQP AKATFAFGAQ

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 93%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against NUP153. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1475 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NUP153

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Alternative Name: NUP153 (NUP153 Products)

Background: Nuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules between the nucleus and cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are pore complex-specific glycoproteins characterized by cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. The protein encoded by this gene has three distinct domains: a N-terminal region within which a pore targeting domain has been identified, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats.
Alias Symbols: HNUP153, N153
Protein Interaction Partner: UBC, HDAC11, LMNA, ESR1, PNPT1, DPY30, FIP1L1, NUP107, NUP54, NUP50, NCAPD2, PRKCSH, MEA1, EIF4B, EEF1B2, CSTF2, C1QBP, CUL3, SIRT7, RANBP2, CTNNB1, XPO7, SUMO2, SMAD3, SUMO1, MAPK3, MAPK1, Mki67, Kifc5b, MYC, KPNB1, tat, APC, USP20, USP11, TPR, SENP2, XP
Protein Size: 1475

Molecular Weight: 162 kDa

Gene ID: 9972

NCBI Accession: NM_005124, NP_005115

UniProt: P49790

Pathways: Protein targeting to Nucleus