GIT2 antibody (C-Term)
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- Target See all GIT2 Antibodies
- GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Dog, Cow, Horse, Pig, Guinea Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GIT2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VQTGSEYTDT SNHSSLKRRP SARGSRPMSM YETGSGQKPY LPMGEASRPE
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 79%
- Characteristics
- This is a rabbit polyclonal antibody against GIT2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product GIT2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 759 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))
- Alternative Name
- GIT2 (GIT2 Products)
- Synonyms
- CAT-2 antibody, CAT2 antibody, cat-2 antibody, xgit2 antibody, git2 antibody, si:dkey-234h16.4 antibody, 1500036H07Rik antibody, 5830420E16Rik antibody, 6430510B20Rik antibody, 9630056M03Rik antibody, B230104M05Rik antibody, mKIAA0148 antibody, zgc:158416 antibody, GIT ArfGAP 2 antibody, G protein-coupled receptor kinase interacting ArfGAP 2 antibody, G protein-coupled receptor kinase interacting ArfGAP 2a antibody, G protein-coupled receptor kinase-interactor 2 antibody, G protein-coupled receptor kinase interacting ArfGAP 2 L homeolog antibody, G protein-coupled receptor kinase interacting ArfGAP 2b antibody, GIT2 antibody, git2 antibody, git2a antibody, Git2 antibody, git2.L antibody, git2b antibody
- Background
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This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined.
Alias Symbols: CAT-2, DKFZp686G01261, KIAA0148, MGC760, CAT2
Protein Interaction Partner: UBC, QPRT, ATF5, CORO1A, HNRNPUL1, TNIP1, CALCOCO2, MVP, RUSC2, SAFB2, IKBKG, SPOP, TSN, TRAF1, TNFAIP3, RCVRN, PROX1, NME2, NFKBIB, SMAD3, LMNB1, KRT18, HGD, GUSB, GCH1, E2F2, C4BPA, ACTN1, ACTG1, Dlg4, POLR1B, USHBP1, RUFY1, SH3GLB2, KCTD5, UBQLN1, EDC4
Protein Size: 759 - Molecular Weight
- 83 kDa
- Gene ID
- 9815
- NCBI Accession
- NM_057169, NP_476510
- UniProt
- Q14161
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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