SDS3 antibody (N-Term)

Catalog No. ABIN2788991

Product Details anti-SDS3 Antibody

Target: SDS3 (SUDS3) (Suppressor of Defective Silencing 3 Homolog (SUDS3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDS3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSAAGLLAPA PAPAAAPAAP EYYPEDEEEL ESAEDDERSC RGRESDEDTE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Suds3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Suds3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SDS3

Target: SDS3 (SUDS3) (Suppressor of Defective Silencing 3 Homolog (SUDS3))

Alternative Name: Suds3 (SUDS3 Products)

Synonyms: RGD1305986 antibody, SAP45 antibody, SDS3 antibody, 2400003N08Rik antibody, 2410008L21Rik antibody, AU067672 antibody, mSds3 antibody, SDS3 homolog, SIN3A corepressor complex component antibody, suppressor of defective silencing 3 homolog (S. cerevisiae) antibody, Suds3 antibody, SUDS3 antibody

Background: Suds3 is a regulatory protein which represses transcription and augments histone deacetylase activity of HDAC1. It may have a potential role in tumor suppressor pathways and may function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
Alias Symbols: 2400003N08Rik, 2410008L21Rik, AU067672, mSds3
Protein Interaction Partner: Tet2, Tet1, Pou5f1, CDK5, Suds3, Sin3b, Sin3a, Cdk5r1,
Protein Size: 328

Molecular Weight: 38 kDa

Gene ID: 71954

NCBI Accession: NM_178622, NP_848737

UniProt: Q8BR65