Cullin 4B antibody (C-Term)

Catalog No. ABIN2789003

Product Details anti-Cullin 4B Antibody

Target: Cullin 4B (CUL4B)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Horse, Rabbit, Guinea Pig, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 4B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IQMKETVEEQ ASTTERVFQD RQYQIDAAIV RIMKMRKTLS HNLLVSEVYN

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Cul4b. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 970 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cullin 4B

Target: Cullin 4B (CUL4B)

Alternative Name: Cul4b (CUL4B Products)

Synonyms: MRXHF2 antibody, MRXS15 antibody, MRXSC antibody, SFM2 antibody, 2700050M05Rik antibody, AA409770 antibody, CUL-4B antibody, mKIAA0695 antibody, RGD1564494 antibody, im:7140950 antibody, im:7150765 antibody, MGC115611 antibody, Tb03.1J15.620 antibody, sfm2 antibody, mrxsc antibody, mrxhf2 antibody, cullin 4B antibody, cullin 4B S homeolog antibody, CUL4B antibody, Cul4b antibody, cul4b antibody, cul4b.S antibody, Tb927.3.1290 antibody

Background: Cul4b is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
Alias Symbols: 2700050M05Rik, AA409770, KIAA0695, mKIAA0695, CUL-4B
Protein Interaction Partner: Nedd8, Eed, Pou5f1,
Protein Size: 970

Molecular Weight: 111 kDa

Gene ID: 72584

NCBI Accession: NM_001110142, NP_001103612

UniProt: A2A432