POLD3 antibody (C-Term)

Catalog No. ABIN2789015

This anti-POLD3 antibody is a Rabbit Polyclonal antibody detecting POLD3 in WB. Suitable for Human, Mouse, Rat, Dog, Pig, Rabbit, Horse, Cow and Guinea Pig.

Quick Overview for POLD3 antibody (C-Term) (ABIN2789015)

Target: POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))

Reactivity: Human, Mouse, Rat, Dog, Pig, Rabbit, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POLD3 Antibody

Binding Specificity: C-Term

Sequence: EEELNMKTSS VHRPPAMTVK KEPREERKGP KKGTAALGKA NRQVSITGFF

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against POLD3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 466 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for POLD3

Target: POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))

Alternative Name: POLD3

Background: The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen, the multisubunit replication factor C, and the 4 subunit polymerase complex: POLD1, POLD2, POLD3, and POLD4.
Alias Symbols: KIAA0039, MGC119642, MGC119643, P66, P68
Protein Interaction Partner: SPRTN, REV1, MAD2L2, UBC, DCP2, PCNA, TSEN2, USP8, POLD4, POLA1, MCM3, APP, NR2C1, RBBP4, HDAC1, DNMT1, CHD4, MTA1, Rel, SUMO2, POLD2, POLD1, MBD3L2, SUMO3, pcn1,
Protein Size: 466

Molecular Weight: 51 kDa

Gene ID: 10714

NCBI Accession: NM_006591, NP_006582

UniProt: Q15054

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA