POLD3 antibody (C-Term)

Catalog No. ABIN2789015

The Rabbit Polyclonal anti-POLD3 antibody (ABIN2789015) specifically detects POLD3 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Pig, Rabbit, Horse, Cow and Guinea Pig samples.

Quick Overview for POLD3 antibody (C-Term) (ABIN2789015)

Target: POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))

Reactivity: Human, Mouse, Rat, Dog, Pig, Rabbit, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POLD3 Antibody

Binding Specificity: C-Term

Sequence: EEELNMKTSS VHRPPAMTVK KEPREERKGP KKGTAALGKA NRQVSITGFF

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against POLD3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 466 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for POLD3

Target: POLD3 (Polymerase (DNA-Directed), delta 3, Accessory Subunit (POLD3))

Alternative Name: POLD3

Background: The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen, the multisubunit replication factor C, and the 4 subunit polymerase complex: POLD1, POLD2, POLD3, and POLD4.
Alias Symbols: KIAA0039, MGC119642, MGC119643, P66, P68
Protein Interaction Partner: SPRTN, REV1, MAD2L2, UBC, DCP2, PCNA, TSEN2, USP8, POLD4, POLA1, MCM3, APP, NR2C1, RBBP4, HDAC1, DNMT1, CHD4, MTA1, Rel, SUMO2, POLD2, POLD1, MBD3L2, SUMO3, pcn1,
Protein Size: 466

Molecular Weight: 51 kDa

Gene ID: 10714

NCBI Accession: NM_006591, NP_006582

UniProt: Q15054

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA