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TSEN2 antibody (C-Term)

TSEN2 Reactivity: Human, Rabbit, Dog, Horse, Cow, Guinea Pig, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2789135
  • Target See all TSEN2 Antibodies
    TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
    Binding Specificity
    • 14
    • 7
    • 2
    • 2
    • 1
    C-Term
    Reactivity
    • 37
    • 17
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rabbit, Dog, Horse, Cow, Guinea Pig, Pig
    Host
    • 35
    • 2
    Rabbit
    Clonality
    • 37
    Polyclonal
    Conjugate
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TSEN2 antibody is un-conjugated
    Application
    • 36
    • 15
    • 13
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    LRRPLSWKSL AALSRVSVNV SKELMLCYLI KPSTMTDKEM ESPECMKRIK
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Pig: 93%, Rabbit: 86%
    Characteristics
    This is a rabbit polyclonal antibody against TSEN2. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product TSEN2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 465 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
    Alternative Name
    TSEN2 (TSEN2 Products)
    Synonyms
    AU067695 antibody, RGD1309946 antibody, PCH2B antibody, SEN2 antibody, SEN2L antibody, tRNA splicing endonuclease subunit 2 antibody, TSEN2 antibody, Tsen2 antibody
    Background
    This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: MGC2776, MGC4440, PCH2B, SEN2, SEN2L
    Protein Interaction Partner: TSEN54, UBC, TBC1D2, PRPF39, POLD3, TBC1D4, TRIP10, USP8, POLD1, Clp1, RANBP10, TSEN15, TSEN34,
    Protein Size: 465
    Molecular Weight
    51 kDa
    Gene ID
    80746
    NCBI Accession
    NM_025265, NP_079541
    UniProt
    Q8NCE0
    Pathways
    Nuclear Receptor Transcription Pathway, Regulation of Lipid Metabolism by PPARalpha
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